16 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... Clinical Manifestations ... #Diagnosis #Management ... #Hematology #SickleCell ... Workup #Algorithm #Ddxof
Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:
Oroya Fever Hematologic ... disease caused ... Lutzomyia verrucarum Clinical ... Nodular → Mular DIAGNOSIS ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... : fever +++, hepatosplenomegaly ... Drugs, Unknown cause ... inhibitors under evaluation ... #management #treatment
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... Causes: - Idiopathic ... , breast CA - Hematologic ... neutrophils in the blood ... #dermatology #oncology
TRALI vs TACO - Transfusion Reactions
TRALI:
 • Epidemiology: 0.1% of transfused patientsl
 • Risk factors: Critical
of high parity blood ... without other cause ... At least 3 of (Acute ... Transfusion #Reactions #hematology ... #diagnosis #comparison
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Aplastic Anemia Clinical ... and petechiae Causes ... result from low blood ... #hematology #diagnosis ... #management
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... Headaches, bone pain, fever ... Lymphadenopathy • HSM • Fevers ... #Leukemia #Hematology ... #Oncology #Diagnosis
Blood Transfusion Reactions

Immune Mediated:
 • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Acute Hemolytic ... S/sx: Fever, flank ... Transfusion Related Acute ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary
Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... S/sx: Fever, flank ... Transfusion Related Acute ... #Transfusions #diagnosis ... #management #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... Lymphadenopathy • Fevers ... ’s lymphoma or acute ... #workup #oncology ... #hematology