13 results
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
liver disease, ... dechallenge • Acute ... ascites), Chronic hepatitis ... • Autoimmune hepatitis ... Diagnosis #Algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... C, A, E, B, D, EBV ... , CMV, HSV • Toxic ... , Acute biliary ... #algorithm #hepatology
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm
Reactive:
 - Systemic Inflammatory
     •
• Rheumatoid Arthritis ... Infectious • EBV ... Tuberculosis • Hepatitis ... Fatigue • Acute ... Algorithm #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... PT, aPTT(liver disease ... - Bone marrow evaluation ... Diagnosis #Causes #Workup ... #hematology
Causes of Knee Effusions - Differential Diagnosis Framework

Knee Effusion Red Flags:
1. Fever/Chills/Joint pain/Night sweats/Weight loss
	- DDX:
		-
, Varicella, EBV ... Parvovirus - Hepatitis ... Reactive Syndrome - Acute ... Effusions: - Hematologic ... Osteochondroma Hematologic
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Acute Liver Injury ... Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... liver #injury #hepatitis ... diagnosis #algorithm #hepatology
Causes of Ascites
Normal Peritoneum
Portal hypertension (SAAG > 1.1 g/dL)
  1. Hepatic congestionl
Liver disease ... - Alcoholic hepatitis ... fibrosis - Acute ... peritonitis - HIV-associated ... #differential #hepatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
), RA, crystal disease ... Inflammatory, crystalline disease ... - parvovirus, HIV ... , hepatitis, herpes ... #approach #workup
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
viral hepatitis ... viral hepatitis ... of cholestatic disease ... Alcoholic liver disease ... #differential #Hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... (RA, Temporal arteritis ... gastric tumors • Hematology ... differential #diagnosis #hematology