10 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... of Sickle Cell Crises ... #Hematology #SickleCell ... Manifestations #Workup ... #Algorithm #Ddxof
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Pregnancy - AFLP ... • Cholestatic disease ... • Alcoholic hepatitis ... • Others #LFTs ... #Hepatology #LiverEnzymes
Liver Chemistries - Interpretation of LFTs

R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP)
 • R >
Interpretation of LFTs ... of cholestatic disease ... Alcoholic liver disease ... #differential #Hepatology ... transaminitis #LFTs
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... gastric bypass), LFT ... (liver disease) ... - Bone marrow evaluation ... #Workup #hematology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... = nonspecific (nausea ... Diagnosis: Viral Hepatitis ... Liver #Pregnancy #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Algorithm Vascular Causes ... Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... liver #injury #hepatitis ... diagnosis #algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
intralobular bile ducts causes ... obstruction • ALP ... Diagnosis: • Viral hepatitis ... cholangitis #diagnosis #workup ... #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... gastric tumors • Hematology ... inflammation (acute ... differential #diagnosis #hematology
Alcoholic Hepatitis - Management Algorithm
Assess Eligibility for Treatment:
 - Maddrey Discriminant Function ≥ (or possibly MELD
Alcoholic Hepatitis ... - Management Algorithm ... exclude other causes ... - Concomitant diseases ... #hepatology
Hepatorenal Syndrome (HRS)

Definition:
• Functional, potentially reversible kidney impairment.
• Occurs in advanced liver disease: cirrhosis, severe alcoholic
advanced liver disease ... severe alcoholic hepatitis ... , or acute liver ... liver transplant evaluation ... Hepatorenal #Syndrome #Hepatology