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diagnosis differential algorithm causes injury transaminitis acute management ascites cirrhosis comparison gastroenterology obstetrics pregnancy saag abnormal aclf aih albumin arthritis
Elevated Liver Function Tests (LFTs) - Differential Diagnosis Framework Mild (<100-500): • NAFLD • Cirrhosis •
Tests (LFTs) - ... Chronic Viral Hepatitis ... Hepatopathy • Acute ... Viral Hepatitis ... Differential #Diagnosis #hepatology
Liver Chemistries - Interpretation of LFTs R-value: Serum (ALT/ULN ALT) / (Alk phos/ULN ALP) • R >
Interpretation of LFTs ... of cholestatic disease ... disease: > 2 ... #differential #Hepatology ... transaminitis #LFTs
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
Causes of Severe Acute ... Liver Injury ... - Drug-Induced liver ... - Wilson disease ... #Differential #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Elevated Liver Enzymes ... • Pregnancy - AFLP ... • Cholestatic disease ... • Others #LFTs ... #Hepatology #LiverEnzymes
Patterns of Liver Injury Transaminase Levels: > 50x normal - Ischemic Hepatitis > 20x normal
Patterns of Liver ... > 20x normal - Acute ... #Patterns #Liver ... #Injury #hepatology ... #LFTs #transaminitis
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... Autoimmune: Autoimmune hepatitis ... Chronic viral hepatitis ... #injury #hepatitis ... diagnosis #algorithm #hepatology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... , Acute biliary ... Syndrome, Celiac Disease ... , Infiltrative Disease ... #algorithm #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework: Liver Injury → liver test abnormalities without evidence of liver
• Infections: Hepatitis ... HELLP, Celiac disease ... Differential #Diagnosis #hepatology ... Transaminitis #LFTs ... #hepatitis
Liver Disease in Pregnancy Intrahepatic Cholestasis of Pregnancy (ICP) • Onset/Trimester: 25-32 weeks • Typical clinical features:
Liver Disease in ... and hemorrhage Acute ... Pregnancy (AFLP) ... #hepatology #obstetrics ... #hepatitis #comparison
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
Acute Fatty Liver ... of Pregnancy (AFLP ... Diagnosis: Viral Hepatitis ... iMedEducation #AFLP ... Pregnancy #hepatology
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