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diagnosis differential rheumatology arthritis sle bleeding bruising comparison disorders druginduced erythematosus gap globulin hemeonc hemophagocytic hemostasis hlh hospitalization joint laboratory
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... disease), HBsAg ... - Bone marrow evaluation ... #Workup #hematology
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
(Morphological Approach ... , Acute blood loss ... : Alcohol use, Liver ... differential #diagnosis #causes ... #hematology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
• Immunologic Workup ... Positive in 60-80% of cases ... of SLE • Evolution ... : Chronic disease ... #Summary #rheumatology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... Usual therapeutic management ... : Chronic disease ... #diagnosis #management
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
inhibitor and lupus ... • Acute DIC ... discern these causes ... disease • Acute ... Differential #Diagnosis #Hematology
Approach to Joint Pain - Diagnostic Framework 1) Chronicity 2) Inflammatory vs Non-Inflammatory 3) Number of Joints Involved 1) Chronicity:
Approach to Joint ... ), RA, crystal disease ... spondyloarthropathies, lupus ... Like in this case ... #approach #workup
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... joint • Systemic lupus ... the presence of anemia ... Screening Tests for Acute ... profile, including liver
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
phlebotomy/ blood work ... during clinical evaluations ... blood loss or acute ... deficiencies • Renal, liver ... of renal disease
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary WHAT? • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Diagnosis and Management ... of unknown cause ... presents with an acute ... • Normocytic anemia ... #Rheumatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... Sarcoidosis) • Liver ... Thalassemia, Sickle cell anemia ... inflammation (acute
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