11 results
Hepatobiliary Manifestations of Sickle Cell Disease
Acute sickle cell hepatic crisis:
 • Fever, acute onset RUQ pain,
of Sickle Cell Disease ... hepatomegaly and anemia ... liver failure ... Hepatobiliary #hepatology ... #hepatitis #differential
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... disease, liver ... (DILI) Viral Hepatitis ... Procedures Management ... Failure #Cirrhosis #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Diagnosis and Workup ... changes), high MCV anemia ... disease), HBsAg ... - Bone marrow evaluation ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... to acute liver ... hepatocellular pattern of liver ... (eg Viral) Management ... #Hepatology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Liver diseases ... and hepatitis ... autoimmune hemolytic anemia ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Diagnostic Scoring System for Wilson's Disease
 - Kayser-Fleischer rings (2 points)
 - Neurological symptoms (2 points)
Coombs-negative hemolytic anemia ... (1 point) - Liver ... the absence of acute ... hepatitis) (2 points ... analysis (4 points) Evaluation
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... the presence of anemia ... Screening Tests for Acute ... IgM) levels • Hepatitis ... profile, including liver
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... Sarcoidosis) • Liver ... Thalassemia, Sickle cell anemia ... inflammation (acute
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
Diagnosis and Management ... presents with an acute ... • An evaluation ... • Normocytic anemia ... #Rheumatology
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
phlebotomy/ blood work ... during clinical evaluations ... blood loss or acute ... deficiencies • Renal, liver ... of renal disease