ddxof evaluation acutepe workup treatment anemia lupus acute management disease diagnosis sle

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Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
• Epidemiology: 10-180/100,000, Typically Age 20-40, F:M

(SLE) - Diagnosis ... • Immunologic Workup ... life-threatening • Treatment ... of SLE • Evolution ... : Chronic disease

Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
• Epidemiology: -10% of all lupus cases, drug-dependent,

• Immunologic Workup ... of SLE • Evolution ... : Chronic disease ... #rheumatology #diagnosis ... #management

Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm

Peripheral Smear concerning for malignancy?

hematology for workup ... Nonmalignant hematologic: Acute ... blood loss, Acute ... infections, TB, Acute ... Severe trauma, Acute

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

SLE (Systemic Lupus ... Classification: • Acute ... Differential Diagnosis ... Pleural effusions • Acute ... lymphopenia, low PLT • Anemia

Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)

Base Disorders - Evaluation ... delta/delta) to see ... the chronicity (acute ... , chronic, or acute ... #workup #Differential

Oroya Fever
Hematologic disease caused by Bartonella bacilliformis
Restricted to the Andes highlands of Peru & Ecuador
B. bacilliformis:

Fever Hematologic disease ... Presentation - Acute ... severe hemolytic anemia ... : • Acute phase ... TREATMENT: • Acute

Algorithm for the Evaluation of Chronic Diarrhea (< 7 days)
Exclude:
1. Causes of acute diarrhea
2. Lactose intolerance
3.

Algorithm for the Evaluation ... Causes of acute ... Systemic disease ... #algorithm #workup ... #diagnosis #differential

Algorithm for Management of Acute Exacerbation of COPD (AECOPD)

Obtain workup for alternate diagnoses and relevant comorbidities:

Algorithm for Management ... of Acute Exacerbation ... AECOPD) Obtain workup ... Lung US, Echo, LE ... #Exacerbation #treatment

Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:

Chronicity: • Acute ... infections (bacterial), acute ... spondyloarthropathies, lupus ... • Acute = Viral ... Chronic = RA, SLE

IgG4-Related Disease
Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor
4 phenotypes:
•

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