12 results
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
Chronicity: • Acute ... spondyloarthropathies, lupus ... Send for cell count ... #rheumatology # ... approach #workup
EULAR/ACR Classification Criteria for Systemic Lupus Erythematosus
Clinical Domains:
 • Constitutional domain: Fever
 • Cutaneous domain: Non-scarring
, Acute cutaneous ... lupusArthritis ... in at least 2 joints ... pericardial effusion, Acute ... nephritis, Class Ill
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Epidemiology: -10% of all ... Constitutional symptoms, Arthritis ... • Immunologic Workup ... • Immunologic Workup ... life-threatening • Treatment
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... Leukemia #diagnosis #workup ... #oncology #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: • Acute ... Pleural effusions • Acute ... : • Joint pain ... arthropathy • 90% joints ... lymphopenia, low PLT • Anemia
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... • Systemic lupus ... the presence of anemia ... Screening Tests for Acute ... #laboratory #workup
Sweet Syndrome

Acute febrile neutrophilic dermatosis (Sweets Syndrome) is a skin condition characterized by fever and inflamed
Sweet Syndrome Acute ... inflammation of the joints ... and pain of the joints ... ’s syndrome - Lupus ... Treatment: - Systemic
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Epidemiology: -10% of all ... Constitutional symptoms, Arthritis ... • Immunologic Workup ... #DIL #rheumatology ... #diagnosis #treatment
Polymyalgia Rheumatica (PMR) Diagnosis and Management Summary

WHAT?
 • Polymyalgia rheumatica (PMR) is a common systemic inflammatory
presents with an acute ... • An evaluation ... for giant cell ... arteritis (GCA) ... • Normocytic anemia
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Albumin > 4) Work-up ... first step in evaluation ... (RA, Temporal arteritis ... anemia • Other ... inflammation (acute