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diagnosis rheumatology erythematosus management ana antinuclear differential druginduced table antibodies autoantibodies classification comparison dil patterns summary treatment vasculitides vasculitis
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
likely it will be clinically ... disease (MCTD), Drug-induced ... (SLE), Systemic ... (SLE), Systemic ... Diseases: Malignancy
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Drug Induced Lupus ... vs SLE Drug Induced ... to 1:1 F:M • Clinical ... months to years) Systemic ... 40, F:M 9:1 • Clinical
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... 40, F:M 9:1 • Clinical ... Workup: - ANA ... • Evolution: ... #lupus #Systemic
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... searched for when ANA ... (60-70%) & drug-induced ... is clinically suspected ... autoantibodies #Systemic
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... extremities Drug ... • Antihistone: Drug ... #Systemic #Lupus
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
< 30 years - Aorta ... branches • GCA: - Aorta ... lupus erythematosus ... LFT • ESR • ANA ... vasculitis, and SLE
Drug Induced Lupus (DIL) • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... Workup: - ANA ... cutaneous-DIL • Evolution
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