9 results
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
Algorithm for the Evaluation ... of Sickle Cell Crises ... Clinical Manifestations ... #Hematology #SickleCell ... Workup #Algorithm #Ddxof
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... Discontinuation of causal ... of SLEEvolution ... #sle #comparison ... #table #rheumatology
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
40, F:M 9:1 • Clinical ... Manifestations: ... Positive in 60-80% of cases ... of SLEEvolution ... #Summary #rheumatology
CNS Manifestations of Systemic Lupus Erythematosus (SLE)

Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
CNS Manifestations ... ) Clinical Manifestations ... autoantibodies that will cause ... CNS #neurology #rheumatology ... cerebritis #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Autoimmune diseases: SLE ... life-threatening manifestations ... inhibitors under evaluation ... Lymphohistiocytosis #diagnosis #management ... treatment #summary #rheumatology
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
to 1:1 F:M • Clinical ... is rare in DIL, SCLE-DIL ... Discontinuation of causal ... #DIL #rheumatology ... diagnosis #treatment #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
manifestation of ... SJIA], systemic lupus ... erythematosus [SLE ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... Manifestations depend ... Diagnosis = clinical ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Relapsing Polychondritis

What is it?
Recurrent inflammation of the cartilage in the body (Autoimmune disorder)

Who?
• Most frequently: 40
manifestation) ... Large vessels (aorta ... such as: • SLE ... Polychondritis #rheumatology ... #diagnosis #management