9 results
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary
 • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
Systemic Lupus Erythematosus ... of SLE versus DIL ... of SLE • Evolution ... #Systemic #Erythematosus ... #Summary #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Evolution: ... months to years) Systemic ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
-1 and IL-6, leading ... lupus erythematosus ... lupus erythematosus ... Syndrome #Diagnosis #Management ... #Hematology #Rheumatology
Adult-Onset Still's Disease
Clinical triad: Fever, Arthralgia/arthritis, Skin rash ± odynophagia
+ Biological inflammation: Increased neutrophils, Hyperferritinemia, decreased
Hantavirus • Malignant ... solid cancers • Systemic ... MAS, Visceral, DIC ... Disease #diagnosis #management ... #treatment #rheumatology
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
autoimmune, infectious, malignant ... IL-6, TNF-a, ? ... episode (30%) Systemic ... Disease #AOSD #rheumatology ... #diagnosis #management
Drug Induced Lupus (DIL)
 • Epidemiology: -10% of all lupus cases, drug-dependent, 4:1 to 1:1 F:M
Drug Induced Lupus ... : -10% of all lupus ... • Evolution: ... #DIL #rheumatology ... diagnosis #treatment #management
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
those coming off aorta ... Remember: Systemic ... vs infection vs malignancy ... them, but urgent rheumatology ... Symptoms #Diagnosis #Management
Sjogren's Syndrome Overview

Epidemiology:
• F > M: 9:1
• 5-6th Decades (can be any age)

Autoimmune exocrinopathy multisystemic disease
• Nephrogenic DI ... Hematologic: ... and Arthritis Malignancy ... Sjogrens #Syndrome #Rheumatology ... #Diagnosis #Management
TAFRO

TAFRO syndrome was first described in 2010, standing for:
- Thrombocytopenia
- Anasarca
- Fever
- Reticulin fibrosis
- Organomegaly

TAFRO syndrome
lupus erythematosus ... with interleukin (IL ... in LNs and the systemic ... TAFRO #diagnosis #management ... #rheumatology #