13 results
Skin Conditions Associated with Joint Pain

Rash
	• Human parvovirus B19 infection

Malar rash
	• SLE
	• Human parvovirus B19 infection
	•
Associated with Joint ... on erythematous base ... lesions • Discoid lupus ... #rashes #differential ... #diagnosis #rheumatology
Approach to Joint Pain - Diagnostic Framework

1) Chronicity
2) Inflammatory vs Non-Inflammatory
3) Number of Joints Involved

1) Chronicity:
spondyloarthropathies, lupus ... Like in this case ... #rheumatology # ... approach #workup ... #differential #
Algorithm for workup of thrombocytopenia based on observation of the peripheral blood film. 
TTP/HUS indicates thrombotic
Algorithm for workup ... thrombocytopenia based ... thrombocytopenia, Hematology ... #Diagnosis #Differential ... Thrombocytopenia #Evaluation
Myositis and Myopathies
Polymyositis 
 • Progressive, symmetric muscle weakness 
 • Elevated CK, +Anti-Jo, +Anti-Mi2
Dermatomyositis
with temporal arteritis ... Anti-retrovirals, Gemcitabine Lupus ... uncommon 5-15% of lupus ... Myopathies #myopathy #differential ... diagnosis #comparison #rheumatology
Approach to Joint Pain

History:
Is the pain from:
	• Joint
	• Adjacent bursa
	• Tendon
	• Ligament
	• Bone
	• Muscle
	• Referred from
• Inflammatory arthritis ... #Pain #MSK #rheumatology ... #approach #workup ... #differential # ... diagnosis #arthritis
Gout (Gouty Arthritis) - MSK Radiology
Imaging Findings:
 • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... interphalangeal joint ... with joint-space ... Differential diagnosis ... diagnosis #msk #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
Constitutional symptoms, Arthritis ... • Immunologic Workup ... cutaneous-DIL • Evolution ... • Immunologic Workup ... comparison #table #rheumatology
Top 10 situations when to think about lupus
1) Inflammatory joint pain (especially in the wrists and
to think about lupus ... ) Inflammatory joint ... the face (many differential ... pericarditis » is...lupus ... erythematosus #rheumatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... Non-autoimmune rheumatologic ... : • Joint pain ... arthropathy • 90% joints ... Erythematosus #Diagnosis #Rheumatology
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases

• Septic arthritis - Gram stain and culture of
Rheumatology Workup ... of the affected joint ... • Systemic lupus ... #laboratory #workup ... diagnosis #testing #Rheumatology