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differential hematology iron nutrition algorithm causes cobalamin testing b12 diarrhea gastroenterology gastrointestinal hepatic hepatology laboratory liverfailure low management mds myelodysplasia
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Anemia of chronic ... kidney disease ... - Vitamin B12 and ... #differential #workup
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
with anemia, diagnose ... inflammation or chronic ... tests Test for celiac ... disease with serology ... #Evaluation #workup
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Elite athletes • Chronic ... Loss (without anaemia ... ): GI cancers, Donations ... Bleeding, Edema, Celiac ... #differential #diagnosis
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Polyphenol / tannins, ↓ Vitamin ... Drugs, H pylori, Celiac ... disease (↑ hepcidin ... #differential #diagnosis ... #anemia #nutrition
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Causes of Low Vitamin ... B12 Levels Low vitamin ... Autoimmune - Pernicious anaemia ... , coeliac disease ... #differential #diagnosis
Chronic Diarrhea - Workup Osmotic: • Consider food diary and trial avoiding certain foods or meds, Consider
Chronic Diarrhea ... - Workup Osmotic ... certain foods or meds ... disease Inflammatory ... #testing #evaluation
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... ) Deficiency Etiology ... related to IBD, celiac ... disease, other ... total body stores Evaluation
Approach to Thrombocytosis - Elevated Platelet Count - Differential Diagnosis Algorithm Peripheral Smear concerning for malignancy?
hematology for workup ... Acute hemolysis, deficiency ... anemia, Rebound ... disease, Kawasaki ... • Infections: Chronic
Commonly Observed Laboratory Findings in Hepatic / Liver Failure - Elevated conjugated and unconjugated bilirubin -
liver disease, ... malabsorption of vitamin ... thrombopoietin deficiency ... can indicate a GI ... Hepatology #Laboratory #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Marrow Failure • Chronic ... Myeloproliferative Disease ... • Nutritional: vitamin ... Myelodysplastic #Syndromes #diagnosis
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