16 results
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... Chronic Myelogenous Leukemia ... disorders • Celiac ... Iron deficiency anemia ... Algorithm #Causes #Hematology
Evaluation and Management of Pediatric Fever #Diagnosis #Management #EM #Peds #Fever #Workup #Evaluation #Discharge #Admission #Algorithm
Evaluation and Management ... of Pediatric Fever ... #Diagnosis #Management ... #EM #Peds #Fever ... Admission #Algorithm #Ddxof
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
uncharacterized fevers ... Consider BCx, CSF evaluation ... #Peds #EM #Classification ... #Fever #SBI #SeriousBacterialIllness ... #Ddxof
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Diagnosis: • Pancytopenia ... if neutropenic fever ... to MDS or acute leukemia ... #diagnosis #management ... #treatment #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... - infiltrates (anemia ... Lymphadenopathy • HSM • Fevers ... #Hematology #Oncology ... #Diagnosis
Bandemia Overview

Normal: < 1%
Clinically significant: > 10%

Band neutrophils are slightly less mature than segmented neutrophils and
Differential Diagnosis ... Tissue damage • Leukemia ... tachycardia or fever ... count on initial evaluation ... neutrophil #WBC #CBC #hematology
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Lymphadenopathy • Fevers ... phenomenon CLL Diagnosis ... • Neutropenia, anemia ... #diagnosis #workup ... #oncology #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
• Most common leukemia ... minimal tumor burden Diagnosis ... ) B symptoms → fevers ... #oncology #hematology ... #hemeonc #diagnosis
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
have had prior evaluations ... Red Flags: • Fever ... infarction • Lymphoma/Leukemia ... bowel syndrome • Celiac ... poisoning • Celiac
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Presentation: • Fever ... recurrent infections/fevers ... virus (EBV) • Leukemia ... #oncology #hematology ... #diagnosis #management