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deficiency differential causes algorithm nutrition hematology b12 cobalamin fe ferritin gastroenterology gastrointestinal gastronintestinal hospitalization lowergibleed management occult pathophysiology pseudoanemia vitamin
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Loss (without anaemia ... ): GI cancers, Donations ... Bleeding, Edema, Celiac ... Disease (IBD, cancer ... #differential #diagnosis
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... with anemia, diagnose ... tests Test for celiac ... disease with serology ... #workup #diagnosis
Causes of Iron Deficiency - Differential Diagnosis Algorithm • Blood loss: GI (cancer, ulcer, IBD), GU
- Differential Diagnosis ... • Blood loss: GI ... Chronic kidney disease ... of absorption): Celiac ... disease, Bypass
Iron Deficiency Anemia - Differential Diagnosis Algorithm Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... • Blood loss: GI ... - Structural: Celiac ... disease, Tropical
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Drugs, H pylori, Celiac ... : Gl lesions / cancer ... : IBD, Chronic disease ... #differential #diagnosis ... #anemia #nutrition
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
skin pallor • GI ... related to IBD, celiac ... disease, other ... total body stores Evaluation ... symptoms • P/E - GI
Occult and Lower Gastronintestinal Bleed - Differential Diagnosis Algorithm Occult (Stool + Occult blood and/or iron deficiency
- Differential Diagnosis ... Occult blood and/or iron ... deficiency anemia ... OUT BRISK Upper GI ... #Differential #Diagnosis
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
during clinical evaluations ... procedures • Iron ... of renal disease ... issues other than GI ... #differential #diagnosis
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
From Blood Cancer ... risk of clonal evolution ... median age at diagnosis ... tolerate anemia ... toxicity from iron
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