11 results
Iron Deficiency Anemia - Differential Diagnosis Algorithm

Labs: Ferritin, iron, transferrin, TIBC, TSAT, sTfR

 • Blood loss:
Anemia - Differential ... Diagnosis Algorithm ... • Blood loss: GI ... - Structural: Celiac ... Algorithm #ferritin #hematology
Gastrointestinal Evaluation of Iron Deficiency Anemia
In patients with anemia, diagnose iron deficiency if:
 • Ferritin <
Gastrointestinal Evaluation ... with anemia, diagnose ... tests Test for celiac ... Gastrointestinal #Evaluation ... #workup #diagnosis
Causes of Thrombocytosis - Differential Diagnosis Algorithm
Spurious:
 • Artifact (redo CBC)
Autonomous:
 • Essential thrombocytosis
 • Polycythemia
- Differential Diagnosis ... disorders • Celiac ... malignancy • Iron ... deficiency anemia ... #Differential #Diagnosis
Causes of Iron Deficiency
 • Inadequate Intake: Vegetarian/vegan diet, Malnutrition
 • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Loss (without anaemia ... ): GI cancers, Donations ... Bleeding, Edema, Celiac ... #differential #diagnosis
Causes of Hyperferritinemia - Differential Diagnosis
Ferritin > 1000
Ferritin is the storage form of iron. Increased hepcidin
- Differential Diagnosis ... cause increased GI ... Hematologic Malignancy ... Sideroblastic anemia ... #Differential #Diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... . pylori test (GI ... changes), high MCV anemia ... - Bone marrow evaluation ... #Differential #Diagnosis
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
skin pallor • GI ... related to IBD, celiac ... total body stores Evaluation ... symptoms • P/E - GI ... consider other diagnosis
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Scleromyxedema (CNS+GI ... Amyloidosis (CVS+PNS+GI ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Differential #Diagnosis
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
during clinical evaluations ... of unnecessary diagnostic ... procedures • Iron ... issues other than GI ... #differential #diagnosis
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
risk of clonal evolution ... median age at diagnosis ... disease tolerate anemia ... toxicity from iron ... #algorithm #hematology