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differential anemia hematology cobalamin algorithm low mcv nutrition alkaline alopecia alp approach dermatology hair hairloss hepatology hyophosphatasia iron loss management
Causes of Vitamin B12 Deficiency - Cobalamin Decreased Intake Pancreas: Insufficiency Intestine: SIBO, Celiac disease, IBD, Lymphoma, Amyloidosis, Resection,
Causes of Vitamin ... B12 Deficiency ... Intestine: SIBO, Celiac ... disease, IBD, Lymphoma ... #B12 #Deficiency
Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Causes of Low Vitamin ... B12 Levels Low ... vitamin B12 intake ... , coeliac disease ... #differential #diagnosis
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... - Differential Diagnosis ... (>100 fL) • B12 ... #Anemia #MCV #Classification ... #Algorithm #Causes
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Causes of Iron Deficiency ... Polyphenol / tannins, ↓ Vitamin ... Drugs, H pylori, Celiac ... disease (↑ hepcidin ... #diagnosis #anemia
Diagnostic Framework for Anemia (Morphological Approach - MCV) Low MCV - <80fL - "Microcytic" • Iron deficiency
Diagnostic Framework ... kidney disease, ... Megaloblastic: Vitamin ... B12 deficiency, ... #causes #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... • B12/Folate ... Disease • Marrow ... Non-lmmune #Anemia #Classification ... #Algorithm #Causes
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
Vitamin B12 (Cobalamin ... • Common Causes ... related to IBD, celiac ... disease, other ... #Deficiency #diagnosis
Allopecia - Differential Diagnosis Framework for Hair Loss Localized / Focal Hair Loss Pattern: • Scarring Alopecia:
- Differential Diagnosis ... Capitis - Skin Disease ... , Vitamin D deficiency ... • Laboratory evaluation ... weight loss • Chronic
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Most cases diagnosed ... thigh bones -> chronic ... Malnutrition • Wilson's disease ... • Vitamin C deficiency ... Pernicious anemia/B12
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Marrow Failure • Chronic ... Myeloproliferative Disease ... • Nutritional: vitamin ... B12 or folic acid ... Myelodysplastic #Syndromes #diagnosis
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