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sle chronic differential erythematosus hematology product reactions summary systemic treatment abdominal algorithm aortic b12 cerebritis cns cobalamin comparison deficiency dissection
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... Positive in 60-80% of cases ... of SLE • Evolution ... : Chronic disease ... #rheumatology
Algorithm for the Evaluation of Chronic Diarrhea (< 7 days) Exclude: 1. Causes of acute diarrhea 2. Lactose intolerance 3.
Algorithm for the Evaluation ... Causes of acute ... Systemic disease ... leukocytes and occult blood ... #workup #diagnosis
CNS Manifestations of Systemic Lupus Erythematosus (SLE) Clinical Manifestations: Demyelinating Syndrome, Headache, Movement disorders, Seizure disorders, Aseptic
Cerebrovascular Disease ... autoantibodies that will cause ... thrombosis and/or blood-brain ... CNS #neurology #rheumatology ... #management #treatment
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
- Differential Diagnosis ... have had prior evaluations ... the patient • Blood ... • Vomiting, diarrhea ... poisoning • Celiac
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Discontinuation of causal ... Usual therapeutic management ... : Chronic disease ... comparison #table #rheumatology ... #diagnosis #management
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Phagocytosis of blood ... Drugs, Unknown cause ... inhibitors under evaluation ... #management #treatment ... #summary #rheumatology
Aortic Dissection Pearls Aortic dissection is caused by a tear in the tunica intima, the innermost layer
dissection is caused ... Evaluation: 1. ... • Aortic valve disease ... ~60 • Control blood ... #management #vascular
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... tongue), abd pain, diarrhea ... related to IBD, celiac ... disease, other ... #management #nutrition
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
Causes purpura & ... TRALI): Leading cause ... cutaneous eruptions, diarrhea ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
Causes purpura & ... TRALI): Leading cause ... cutaneous eruptions, diarrhea ... #Transfusions #diagnosis ... #management #hematology
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