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differential hematology management cardiology deficiency rheumatology sle algorithm b12 cobalamin disorders druginduced effusion erythematosus gap gastroenterology gastrointestinal globulin hemopericardium hemorrhagic
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... , diagnose iron ... tests Test for celiac ... disease with serology ... #workup #diagnosis
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
• Immunologic Workup ... • Immunologic Workup ... : Chronic disease ... #sle #comparison ... #rheumatology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential Diagnosis ... and Workup History ... changes), high MCV anemia ... - Bone marrow evaluation ... #Causes #Workup
Systemic Lupus Erythematosus (SLE) - Diagnosis and Management Summary • Epidemiology: 10-180/100,000, Typically Age 20-40, F:M
(SLE) - Diagnosis ... • Immunologic Workup ... Positive in 60-80% of cases ... : Chronic disease ... Erythematosus #Diagnosis
Causes of Pericarditis - Differential Diagnosis Algorithm Viral: • Coxsackie • Echovirus • Adenovirus • Epstein-Barr virus
Causes of Pericarditis ... - Differential Diagnosis ... arthritis • Systemic lupus ... connective tissue disease ... #Cardiology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory Evaluation ... hallmark for the disease ... result in severe anemia ... immune hemolytic anemia ... #Workup #Hematology
Hemorrhagic Pericardial Effusions (Hemopericardium)- Differential Diagnosis Framework IATROGENIC DISEASE Secondary to invasive cardiac procedures NONIATROGENIC • Malignancy (e.g., metastatic spread:
- Differential Diagnosis ... IATROGENIC DISEASE ... OTHER RARE CAUSES ... induced • MCTD, Lupus ... #cardiology
Vitamin B12 (Cobalamin) Deficiency Etiology: • Vit B12 - aka cobalamin. Present in foods derived from animal
• Common Causes ... related to IBD, celiac ... disease, other ... total body stores Evaluation ... consider other diagnosis
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
phlebotomy/ blood work ... during clinical evaluations ... of unnecessary diagnostic ... of renal disease ... #differential #diagnosis
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... first step in evaluation ... • Heavy chain disease ... Thalassemia, Sickle cell anemia ... #differential #diagnosis
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