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differential causes hematology algorithm gastroenterology iron nutrition workup cardiology cobalamin dermatology diarrhea pediatrics pressure pulse systemic thrombocytosis alopecia approach atlas
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... with anemia, diagnose ... inflammation or chronic ... tests Test for celiac ... disease with serology
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Diagnostic Algorithm ... - Iron deficiency ... - Anemia of chronic ... kidney disease ... Probable bone marrow disorder
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia, Chronic ... disease anemia ... Unstable hemoglobin disorders ... myeloma Rouleaux: Chronic ... #differential #diagnosis
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Drugs, H pylori, Celiac ... disease (↑ hepcidin ... Iron metabolism disorders ... #differential #diagnosis ... #anemia #nutrition
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... • Rheumatic disorders ... • Celiac disease ... malignancy • Iron deficiency ... anemia #Thrombocytosis
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... • RBC Membrane Disorder
Causes of Iron Deficiency • Inadequate Intake: Vegetarian/vegan diet, Malnutrition • Increased Body Needs: Infants/preschoolers, Pregnancy,
Causes of Iron Deficiency ... Elite athletes • Chronic ... Loss (without anaemia ... Bleeding, Edema, Celiac ... #differential #diagnosis
Causes of Wide Pulse Pressure - Differential Diagnosis Physiologic: • Advanced age-arteriosclerosis (less compliant arteries) • Well
- Differential Diagnosis ... - Severe iron deficiency ... - Chronic pulmonary ... diseases • Arteriovenous ... #causes #cardiology
Hypocalcemia Laboratory Evaluation Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Hypocalcemia Laboratory Evaluation ... differentiate between disorders ... - Vitamin D deficiency ... - Chronic kidney ... disease #Hypocalcemia
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 Causes of Low Vitamin B12 Levels Low vitamin B12 intake - Vegetarianism, chronic alcoholism and older people Autoimmune
Autoimmune - Pernicious anaemia ... , coeliac disease ... Transcobalamin II deficiency ... #VitaminB12 #deficiency ... #differential #diagnosis
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