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differential hematology causes algorithm anemia workup bleeding cardiology diarrhea iron nutrition pediatrics pressure pulse thrombocytosis alopecia approach atlas b12 basophilia
Causes of Thrombocytosis - Differential Diagnosis Algorithm Spurious: • Artifact (redo CBC) Autonomous: • Essential thrombocytosis • Polycythemia
- Differential Diagnosis ... : • Acute or Chronic ... • Rheumatic disorders ... • Celiac disease ... malignancy • Iron deficiency
Anemia - Underproduction Diagnostic Algorithm - Iron deficiency anemia - Anemia of chronic inflammation - Anemia
Underproduction Diagnostic ... - Anemia of chronic ... - Anemia of chronic ... kidney disease ... Probable bone marrow disorder
Causes of Iron Deficiency • Diet: ↓ Intake, e.g. vegan, Malnutrition, Polyphenol / tannins, ↓ Vitamin
Drugs, H pylori, Celiac ... Inflammation: IBD, Chronic ... disease (↑ hepcidin ... Iron metabolism disorders ... #differential #diagnosis
Gastrointestinal Evaluation of Iron Deficiency Anemia In patients with anemia, diagnose iron deficiency if: • Ferritin <
Gastrointestinal Evaluation ... patients with anemia, diagnose ... inflammation or chronic ... tests Test for celiac ... disease with serology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
Malabsorption (e.g. celiac ... disease, CF, IBD ... Malignancy, Autoimmune disorders ... table #comparison #diagnosis ... #hematology #deficiency
Hypocalcemia Laboratory Evaluation Serum levels of PTH, phosphorus, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D can help differentiate between
Hypocalcemia Laboratory Evaluation ... differentiate between disorders ... - Vitamin D deficiency ... - Chronic kidney ... disease #Hypocalcemia
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 Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
anemia, Chronic ... Unstable hemoglobin disorders ... myeloma Rouleaux: Chronic ... #differential #diagnosis ... #hematology #microscopy
Overall Approach to Anemia - Differential Diagnosis Algorithm Blood Loss • Acute Bleed - Normocytic / Normochromic
- Differential Diagnosis ... RBCs on Smear • Chronic ... • Anemia of Chronic ... Disease • Marrow ... • RBC Membrane Disorder
Causes of Failure to Thrive - Differential Diagnosis Algorithm Adequate Calorie Consumption - Increased Losses:
- Differential Diagnosis ... Fibrosis) • Celiac ... Disease • ... • Metabolic Disorders ... Algorithm #Causes #Peds
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
- Differential Diagnosis ... administration, evaluation ... The appropriate evaluations ... #Differential #Diagnosis ... #Hematology
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