10 results
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Can present in middle ... to 8 years Clinical ... disease • Infectious ... autoimmune hemolytic anemia ... DDX - Other causes
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
BCNIE relies on evaluation ... antimicrobials, clinical ... but important causes ... ribosomal RNA PCR ... - PCR for
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
should be based on clinical ... presentation, temporal evolution ... present in 15% of cases ... Demyelinating disease caused ... • JC-virus PCR
Anemia of Hospitalization - Pathophysiology

Why does the Hgb/Hct drop in the first two days during hospitalization?

Interestingly,
from injuries and infections ... the Journal of Clinical ... reasoning during clinical ... evaluations. ... prolonged rest can cause
Lung Abscess - Diagnosis and Management Summary

Lung Abscess Etiology:
 • Necrosis of lung parenchyma by a
polymicrobial infection ... • Most common cause ... Lung Abscess - Clinical ... Leukocytosis, anemia ... of PCN allergy
Nontuberculous Mycobacteria (NTM) Infections 

Mycobacterial species other than those belonging to the Mycobacterium tuberculosis complex and
status NTM Cause ... Syndrome of right middle ... Bone Marrow - Anemia ... Pulmonary Disease: Clinical ... Lung Disease: • Clinical
Fever After International Travel

Infectious Disease:
• Endemic in either the destination or home region

Viral Syndromes:
Arboviral infections, a
, a common cause ... No hemolytic anemia ... polymerase-chain-reaction (PCR ... testing of a saliva sample ... , and possibly PCR
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
first step in evaluation ... Causes of Monoclonal ... Include: • Viral infections ... Thalassemia, Sickle cell anemia ... • Other causes
Summary of Monkeypox: Current Knowledge as of May 2022
 • What is Monkeypox?
 • Origins of
period (time from infection ... 5–21 days • Clinical ... - Case-fatality ... • Diagnosis: PCR ... lesions (ideally sample
Babesiosis on Peripheral Smear
85 M from SE USA, hx splenectomy, IgG4 plasmacytic syndrome: F, chills, profound
Ab IFA 1:256, PCR ... inclusions, improved clinically ... lysis: fever, anemia ... ARDS and DIC, case ... Indiana University Infectious