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diabetes dka management pharmacology comparison diabeticketoacidosis hyperglycemic pathophysiology summary agonists aniongap classification crisis diabetic diagnosis differential disorders dmii dosing dpp4
Pathophysiology of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) Absolute Insulin deficit: - Type I DM:
Hyperosmolar Syndrome (HHS ... Polydipsia #dka #hhs ... pathophysiology #comparison #endocrinology ... #diabetes #diabetic ... #ketoacidosis #
Hyperglycemic Crisis - Algorithm for DKA/HHS Diagnostic criteria for DKA: • pH < 7.3 • Anion gap
Hyperglycemic Crisis - Algorithm ... Hyperglycemic #Crisis #Algorithm ... #management #endocrinology ... #Diabetes #DM2 ... #Ketoacidosis
Type 2 Diabetes - Screening, Diagnosis and Management Algorithm Lifestyle Modifications (Diet and Exercise) -> Start
and Management Algorithm ... qhs (D/C Secretagogues ... relative with DM2 ... • Secondary Causes ... Targets #Management #algorithm
Diabetes Mellitus Type 2 Inpatient Medication Guide Classes: Biguanide, Sulfonylurea, TZD, DPP-4 inhibitor, GLP-1 receptor agonist, SGLT2i,
Diabetes Mellitus ... Medication Guide Classes ... in Type 1 Diabetes ... #Mellitus #DM2 ... comparison #table #endocrinology
Ketosis Disorders Ketone bodies are a normal metabolic energy source. Excessive unregulated production of ketones, often accompanied
• Alcoholic ketoacidosis ... • Diabetic ketoacidosis ... (DKA) - caused ... Glucosuria causes ... diagnosis #management #endocrinology
Metformin Pharmacology Summary Mechanisms of Action: • Suppresses gluconeogenesis by the liver • Increases insulin-mediated glucose utilization
• Increases insulin-mediated ... agent • Does not cause ... e.g. diarrhea, nausea ... Pharmacology #Summary #DM2 ... #diabetes #endocrinology
DKA DIAGNOSTIC CRITERIA: 1. Serum glucose >250 mg/dL 2. Arterial pH <7.3 3. Serum bicarbonate <18 mEq/L 4. At least
patients with type 2 diabetes ... have new-onset diabetes ... Continue insulin ... and acidosis has ... #DKA #EDKA #Insulin
Diabetic Ketoacidosis (DKA) - Pathogenesis and Clinical Findings • Note: in DKA, body K+ is lost
Diabetic Ketoacidosis ... out of cells may cause ... ensure patient has ... pathophysiology #endocrinology ... #diabetes
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
-> Stimulates Insulin ... will stimulate insulin ... This drug class has ... Pharmacology #Management #Diabetes ... #DM2 #Endocrinology
GLP-1 Receptor Agonists - Pharmacology Summary Mechanisms of Action: Stimulate glucose-dependent insulin release from the pancreas (GLP-1
glucose-dependent insulin ... e.g. diarrhea, nausea ... not definitively cause ... Pharmacology #Summary #DM2 ... #diabetes #endocrinology
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