11 results
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Acute-on-Chronic ... #Acute #Chronic ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... Symptomatic anemia Diagnosis ... progress to MDS or acute ... #management #treatment ... #hematology
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
Signs of severe ... Anesthesiology #Anesthesia ... #Intraoperative ... #Checklist #Diagnosis ... #Management #Workup
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
and Management ... Management: • ... D/c all heparin ... , Bivalirudin, DOAC ... #Hematology #HemeOnc
Intraoperative Anaphylaxis - Guidelines for Crises in Anaesthesia
• Unexplained hypotension
• Unexplained bronchospasm (wheeze may be absent
Intraoperative Anaphylaxis ... of more of the signs ... pack. ❸ Remove all ... #Checklist #Diagnosis ... #Management #Workup
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Presentation: Subacute-Acute ... • Rare: DAH, acute ... , Anaphylaxis, Acute ... #management #hematology
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... , AKI, acute limb ... WBC >100k, + lab signs ... Syndrome #TLS #diagnosis ... #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... present, symptoms, signs ... transformation into AML ... #Management #Summary ... #treatment #hematology
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... presents as an acute ... Diagnosis via genetic ... #management #treatment ... #hematology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
subclinical disease to acute ... , AIH diagnosis ... Anti-LKM & Anti-ALC ... Hepatitis (eg Viral) Management ... #Management #Hepatology