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oncology hepatology rheumatology algorithm differential treatment hemeonc hemophagocytic hlh leukemia lymphohistiocytosis summary workup abnormal anesthesiology anticoagulation antiphospholipid aps autoantibodies behcet
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Score • CML -> AML ... • Tumor lysis syndrome ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... Incidence: common in APL ... : >3 symptoms, or ... #APML #diagnosis ... #management #hematology
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Anti-cardiolipin (aPL ... - Anti-B2GP1 (aPL ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Antiphospholipid Syndrome (APS) APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
Antiphospholipid Syndrome ... Antiphospholipid antibodies (aPL ... Anticardiolipin antibodies (aCL ... target to 3-4 • DOACs ... #management #anticoagulation
Polycythemia Vera (PV) - Diagnosis and Management Summary Diagnostic Criteria: • Elevated hemoglobin and/or hematocrit AND •
and Management ... , signs, and complications ... transformation into AML ... #Management #Summary ... #treatment #hematology
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Dehydration • Symptoms ... have fever - ACS ... WBC >100k, + lab signs ... #TLS #diagnosis ... #management #hematology
Intraoperative Hypertension - Guidelines for Crises in Anaesthesia Hypertension is most commonly due to inappropriate depth of
reservoir bag and APL ... alfentanil can be diagnostic ... overload / TURP syndrome ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Post-Transplantation Lymphoproliferative Disorders (PTLD) Definition: Lymphoid and/or plasmacytic proliferations that occur as a result of immunosuppression in
accounts for 21% of all ... Conditioning regimen Signs ... , unexplained hematologic ... EBV viral load, signs ... #management #transplant
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... Care focuses on symptom ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... #diagnosis #management ... #signs #symptoms ... #rheumatology #
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