15 results
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
) 30-45% Differential ... Diagnosis and Lupus ... autoantibodies #signs ... symptoms #mimickers #differential ... #rheumatology
Drug Induced Lupus vs SLE
Drug Induced Lupus (DIL):
 • Epidemiology: -10% of all lupus cases, drug-dependent,
constitutional symptoms • Treatment ... life-threatening • Treatment ... Usual therapeutic management ... comparison #table #rheumatology ... #diagnosis #management
Antiphospholipid Syndrome (APS)
APS is a rare autoimmune disorder characterized by recurring blood clots resulting from antibodies
): • Lupus anticoagulant ... Anticardiolipin antibodies (aCL ... to be present Treatment ... target to 3-4 • DOACs ... #management #anticoagulation
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
and Management ... present, symptoms, signs ... transformation into AML ... #Management #Summary ... #treatment #hematology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
and Management ... D/c all heparin ... , Bivalirudin, DOAC ... #Management #Treatment ... #Hematology #HemeOnc
Leukostasis vs Tumor Lysis Syndrome
Leukostasis:
 • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
have fever - ACS ... WBC >100k, + lab signs ... organ damage • Treatment ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... Triggers: ATRA treatment ... initiation • Differential ... Renal Failure Treatment ... #management #hematology
It is important to recognize Acute Decompensated Heart Failure (ADHF) as more than just simply a
Signs of poor perfusion ... Signs of congestion ... #diagnosis #differential ... #algorithm #management ... icu #clinical #pharmacology
Peripartum Cardiomyopathy - Summary
1. Definition
 • Towards the end of pregnancy to 5 months postpartum
Differential Diagnosis ... Avoid Warfarin and DOAC ... should be done on diagnosis ... Cardiomyopathy #diagnosis ... #treatment
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... very remarkable w/differential ... Treatment of GCA ... them, but urgent rheumatology ... #Management