57 results
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
skin thickening Signs ... (interstitial lung ... scleroderma renal crisis ... #signs #symptoms ... #testing #workup
Peri-operative Hyperthermia - Guidelines for Crises in Anaesthesia
If prolonged or ≥ 39 C this is a
39 C this is a clinical ... (late sign) (→ ... #Hyperthermia #Differential ... Anesthesia #Checklist #Diagnosis ... #Management #Workup
Maculopapular - Diagnostic Algorithm
Pathophysiology:
- Catch-all term with a wide range of potential pathophysiologic mechanisms and causative
Maculopapular - Diagnostic ... : - Catch-all term ... Ill-appearing, vital sign ... Immunocompromised #Diagnosis ... Targetoid #Algorithm #Differential
Tree in Bud Sign
The Tree-in-Bud sign represents Endobronchial spread in a linear branching pattern and centrilobular
Tree in Bud Sign ... The Tree-in-Bud sign ... Bud #TreeInBud #Sign ... #diagnosis #clinical ... radiology #ChestCT #pathophysiology
Myasthenic Crisis Checklist - Myasthenia Gravis

Evaluation 
 - Chest X-ray and lung ultrasound (exclude other lung
Myasthenic Crisis ... Phos), CBC with differential ... - Infectious workup ... Pyridostigmine - New diagnosis ... monitoring (vital signs
Major neurocognitive disorders (MNCD): Diagnosis and workup 

1) Clinical diagnosis Cognitive impairment + loss of autonomy
2)
and workup ... 1) Clinical diagnosis ... (parkinsonian signs ... MNCD #Dementia #Differential ... #Workup
Local Anaesthetic Toxicity - Guidelines for Crises in Anaesthesia
Signs of severe toxicity:
 • Sudden alteration in
in Anaesthesia Signs ... inform immediate clinical ... ensure adequate lung ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Malignant Hyperthermia Crisis - Guidelines for Crises in Anaesthesia
Unexplained increase in ETCO2 AND tachycardia AND increased
rise is a late sign ... hyperventilate lungs ... Plan admission to critical ... Intraoperative #Checklist #Diagnosis ... #Management #Workup
Retinoblastoma: Pathogenesis and clinical findings
 • Sporadic mutation -> One allele of RB1 tumor suppressor gene
Pathogenesis and clinical ... Retinoblastoma Signs ... Retinoblastoma #pathophysiology ... ophthalmology #diagnosis ... #signs #symptoms
Acute Rheumatic Fever: Pathogenesis and Clinical Findings

Delayed autoimmune reaction
-> Molecular mimicry
-> GAS antigen cross-reacts with host
->
Pathogenesis and Clinical ... -> GAS antigen cross-reacts ... RheumaticFever #pathophysiology ... #diagnosis #signs