14 results
Aplastic Anemia - Illness Script
Signs and symptoms:
 • Recurrent infections from neutropenia
 • Mucosal bleeding from
Illness Script Signs ... : • Recurrent infections ... Diagnosis: • Pancytopenia ... Treatment: • Consider ... #diagnosis #management
Suspected Celiac Disease - Diagnosis Algorithm

Celiac disease suspected:
 • Signs and symptoms of celiac disease
 •
suspected: • Signs ... disease • Iron-deficiency ... anemia unresponsive ... to treatment ... NSAlDs, ARBs) • Infection
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... Cellular immune deficiency ... Unknown cause Treatment ... #management #treatment
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
, GATA2 deficiency ... , CTLA4 deficiency ... Treatment: ... oncology #hematology #diagnosis ... #management
Hemophagocytic Lymphohistiocytosis (HLH)
Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... can mimic common infections ... Ferritin >500 ng/mL ... : • Infection ... #management #treatment
Vitamin B12 (Cobalamin) Deficiency
Etiology:
 • Vit B12 - aka cobalamin. Present in foods derived from animal
B12 (Cobalamin) Deficiency ... level (< 200 pg/mL ... Check for IF ab Treatment ... consider other diagnosis ... #diagnosis #management
Mycoses

HISTOPLASMOSIS
• Inhalation of conidia → Yeast → travel to lymph nodes → spread in body
• Bird
Histoplasmosis Diagnosis ... transplantation • MCC ... MC: CNS CSF: • ... ) #Mycoses #InfectiousDiseases ... #Management #Infections
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
petechiae) • Frequent infections ... or folic acid deficiency ... • Parvovirus infection ... • Copper deficiency ... Myelodysplastic #Syndromes #diagnosis
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
bouts of HTN Diagnostic ... • Bilateral signs ... • Nutritional Deficiency ... Transverse Myelitis Treatment ... #management #neurology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
systemic sx + signs ... vasculitis vs infection ... systemic complaints- anemia ... Treatment of GCA ... #Management