7 results
Multiple Sclerosis - Summary

Multiple Sclerosis (MS) is an autoimmune-mediated neurodegenerative disease of the central nervous system
Multiple Sclerosis ... Sclerosis Diagnosis ... Signs and symptoms ... criteria for MS ... #sclerosis #diagnosis
Spinal Cord Disorders - Differential Diagnosis Framework

Spinal cord neurological lesion:
Clinical findings:
 • Symptoms and signs below
- Differential Diagnosis ... and signs below ... Demyelinating: - Multiple ... sclerosis - Transverse ... Scleroderma, Systemic sclerosis
Amyotrophic Lateral Sclerosis (ALS) Summary
ALS: combination of the clinical examination finding of amyotrophy with the pathologic
Pathophysiology ... brainstem and multiple ... spinal cord regions ... fasciculations Common Symptoms ... #neurology #diagnosis
Transverse Myelitis Overview

Focal inflammatory disorder of the spinal cord resulting in rapid onset of weakness, sensory
monophasic Pathophysiology ... Criteria: • Sensory ... • Bilateral signs ... and/or symptoms ... sclerosis, NMOSD
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
lumbar spine • MCC ... spine L1-L5 Symptoms ... so-called ‘red flag’ symptoms ... Differential Diagnosis ... : • Spinal cord
Stiff Person Syndrome (SPS) - Diagnosis and Management Summary

Epidemiology:
 • Prevalence: 1-2 cases per million -
Person Syndrome Pathophysiology ... brain and spinal cord ... Anti-GAD Ab (>1000u/ml ... Parkinson's disease, Multiple ... sclerosis, Ankylosing
Evaluation of Recurrent Falls

Core Concept:
Maintaining an upright posture requires the integrated function of multiple systems.
Disruption in
Recurrent Falls Core ... presyncope, exertional symptoms ... positive Romberg sign ... sclerosis • Clues ... Recurrent #Falls #Diagnosis