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hematology management differential lupus sle systemic dermatology dermatomyositis hodgkins leukemia lymphoma vasculitis antimda5 antimda5dm antinxp2 antinxp2dm arthritis autoantibodies behcet chronic
Rheumatoid Arthritis Summary MCP and PIP Involvement, Spares DIP, Carpal Tunnel, Sicca Syndrome, Epi/Scleritis, Heart Disease, Rheumatoid
Arthritis Summary MCP ... Scleritis, Heart Disease ... Arthritis #RA #diagnosis ... #rheumatology # ... signs #symptoms
Systemic Lupus Erythematosus - Diagnosis Manifestations: - Arthritis 69% - Malar rash 40% - Fever 36% -
Systemic Lupus Erythematosus ... sclerosis, Still's disease ... Systemic #Lupus #Erythematosus ... #signs #symptoms ... #differential #rheumatology
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison Hodgkin's Lymphoma: • Epidemiology: young adults 20-30, older 50-70 •
translocation • Types: Classification ... Differential Diagnosis ... Malignancies (eg CML ... NonHodgkins #comparison #oncology ... #hematology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Induced Lupus: • Symptoms ... #Diagnosis #Rheumatology
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
pain (20%) Renal disease ... SLE #systemic #erythematosus ... #signs #symptoms ... #diagnosis #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
CNS symptoms (headache ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
systemic lupus erythematosus ... Presentation - Systemic Symptoms ... purpura: strong sign ... #rheumatology # ... classification
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
rapid onset of symptoms ... chronic onset of symptoms ... extramedullary disease ... #Leukemia #Hematology ... #Oncology #Diagnosis
ANTI-MDA5 DERMATOMYOSITIS Cutaneous manifestations: • Periorbital heliotrope (blue-purple) rash with edema • Erythematous rash on the face, or the
with edema • Erythematous ... dorsal part of the MCP ... severity of the disease ... Dermatomyositis #rheumatology ... #dermatology #diagnosis
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
age, however the disease ... : HLH signs and ... symptoms can mimic ... Ferritin >500 ng/mL ... management #treatment #hematology
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