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hematology syndrome hemophagocytic hlh lymphohistiocytosis apml behcet classification differentiation disease fungal hemeonc hodgkins infections infectiousdiseases leukostasis lymphoma lysis mycoses tafro
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... Lysis Syndrome: • Pathophysiology ... Syndrome #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... opacities • Diagnosis ... : >3 symptoms, or ... #management #hematology ... #oncology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
CNS symptoms (headache ... artery aneurysms Diagnosis ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... symptoms can mimic ... Ferritin >500 ng/mL ... #management #treatment ... #hematology
Mycoses HISTOPLASMOSIS • Inhalation of conidia → Yeast → travel to lymph nodes → spread in body • Bird
• Rheumatologic ... transplantation • MCC ... MC: CNS CSF: • ... Aspergillosis Pathophysiology ... #Management #Infections
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
ingestion • B symptoms ... classical HL (MCHL ... lymph node biopsy (diagnostic ... Hodgkins #lymphoma #diagnosis ... #oncology #management
TAFRO TAFRO syndrome was first described in 2010, standing for: - Thrombocytopenia - Anasarca - Fever - Reticulin fibrosis - Organomegaly TAFRO syndrome
cell lymphoma Pathophysiology ... and the systemic symptoms ... Histopathological Diagnoses ... agonists #TAFRO #diagnosis ... #management #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... Presentation • Common Signs ... and Symptoms: ... Pathophysiology ... #Management #Hematology
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