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treatment associations autoantibodies comparison hemophagocytic hlh lupus lymphohistiocytosis summary syndrome thrombocytopenia activation antibodies antinxp2 antinxp2dm behcet coagulation deficiencies deficiency dermatology
Autoantibodies in Rheumatology • Lupus (SLE): ANA (anti-nuclear antibody), dsDNA (double-stranded DNA), Anti-Smith, Anti-Ro (SSA) and
Autoantibodies in Rheumatology ... • Lupus (SLE): ... Autoantibodies #Rheumatology ... #diagnosis #associations ... #table
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
RA Anti-dsDNA - SLE ... - Drug-induced SLE ... syndrome Anti-Scl ... Associations #diseases #diagnosis ... #table #rheumatology
Summary of Coagulation Deficiencies Inherited: • Hemophilia A - Deficiency of Factor VIII • Hemophilia B -
LMWH, warfarin, DOACs ... RA, SLE), Post-partum ... Deficiencies #Summary #table ... #comparison #diagnosis ... #hematology #deficiency
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
Induced Lupus vs SLE ... Usual therapeutic management ... #comparison #table ... #rheumatology # ... diagnosis #management
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook Presentation: • Plts ↓50% (nadir
and Management ... Confirmatory test ↑Se ... Management: • ... , Bivalirudin, DOAC ... #Hematology #HemeOnc
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
) Differential Diagnosis ... Oral aphthae : SLE ... • Arthritis: SLE ... #management #signs ... #symptoms #rheumatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Skin Disease Classification ... Differential Diagnosis ... Non-autoimmune rheumatologic ... Malignancy (e.g. hematologic ... #Rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Ferritin >1000 ng/ml ... sIL-2R >2400 Ul/ml ... Autoimmune diseases: SLE ... #management #treatment ... #summary #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: HLH signs and ... Diagnosis via genetic ... Ferritin >500 ng/mL ... #management #treatment ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
-95% of cases) Classification ... classical HL (MCHL ... #classification ... #hematology #oncology ... #management
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