16 results
Adult-Onset Still's Disease (AOSD)
Rare inflammatory disorder of unknown etiology, difficult to diagnose because of heterogenous presentation.
Adult-Onset Still's Disease ... episode (30%) Systemic ... low ferritin, arthritis ... #AOSD #rheumatology ... #diagnosis #management
Systemic Sclerosis (Scleroderma)
Multi-system autoimmune disease characterized by vasculopathy and progressive fibrosis of skin and internal organs
3
autoimmune disease ... and Symptoms: ... Scleroderma #SSc #rheumatology ... #diagnosis #signs ... #workup
Clinical Features of Systemic Lupus (SLE)
General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%)
Eye: Sjögrens (15%)
Skin
of hip (rare), Arthritis ... pain (20%) Renal disease ... erythematosus #signs ... #symptoms #diagnosis ... #rheumatology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
idiopathic arthritis ... erythematosus [SLE], AOSD ... Activation #Syndrome #Diagnosis ... #Management #Hematology ... #Rheumatology
Systemic Lupus Erythematosus - Diagnosis
Manifestations:
 - Arthritis 69%
 - Malar rash 40%
 - Fever 36%
 -
Systemic Lupus Erythematosus ... : - Arthritis ... autoantibodies #signs ... #symptoms #mimickers ... #differential #rheumatology
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
Behçet's Syndrome Systemic ... meningitis), MCC CNS symptoms ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
Giant cell arteritis (GCA)

Giant cell arteritis (GCA) definition: Most common systemic inflammatory vasculitis in older adults
signs/sx of inflammation ... them, but urgent rheumatology ... GCA #Temporal #Signs ... #Symptoms #Diagnosis ... #Management
Adult Onset Still's Disease
Systemic inflammation with urticarial rash.
Rash: 
 • Nonpruritic, evanescent (correlates with time of
Systemic inflammation ... the chest/trunk Symptoms ... #AOSD #diagnosis ... #rheumatology # ... management
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
- Differential Diagnosis ... Differential Diagnosis ... Symptoms (Sx) in ... purpura: strong sign ... #rheumatology #
Vasculitis - Differential Diagnosis Framework

When to Consider Vasculitis:
• Purpura, ischemic skin lesions
• Mononeuritis multiplex
• Hematuria, proteinuria,
- Differential Diagnosis ... Symptoms (SX) in ... purpura: Strong sign ... • Progressive symptoms ... #Rheumatology