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rheumatology differential symptoms vasculitis apml arthritis classification differentiation hemeonc hemophagocytic hlh leukostasis lymphohistiocytosis lysis oncology ra rheumatoid sarcoidosis sjogrens tls
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
Leukostasis: • Pathophysiology ... WBC >100k, + lab signs ... : • Pathophysiology ... #TLS #diagnosis ... #management #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... ATRA treatment Pathophysiology ... Imaging: CXR- pulmonary ... Anaphylaxis, Acute Renal ... #management #hematology
Sarcoidosis - Diagnosis and Management Summary Epidemiology 1) High incidence in Scandinavian countries (11-24 cases per 100,000 individuals
and Management ... survival is 93-95% Pathophysiology ... , and possibly renal ... Pulmonary: dyspnea ... #Management #Signs
Vasculitis and Vasculitides - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions •
- Differential Diagnosis ... and renal abnormalities ... purpura: strong sign ... • Urinalysis (Renal ... #rheumatology #
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
, INC risk PE, Pulmonary ... cirrhosis: 3%-20% Renal ... Distal (Type I) renal ... Nephrogenic DI Hematologic ... Diagnosis #Management
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
- Differential Diagnosis ... and renal abnormalities ... Vasculitis Differential Diagnosis ... purpura: Strong sign ... #Rheumatology
Rheumatoid Arthritis - Signs and Symptoms • Ocular: Keratoconjunctivitis sicca, Episcleritis, Scleritis, Scleromalacia perforans • Pulmonary:
Scleromalacia perforans • Pulmonary ... Pericarditis • Renal ... Thrombocytosis, Felty's syndrome ... #Symptoms #diagnosis ... #rheumatology
Hemophagocytic Lymphohistiocytosis (HLH) High mortality without prompt recognition and management. HLH is a critical diagnostic consideration in
recognition and management ... hyperinflammatory syndrome ... Presentation • Common Signs ... Pathophysiology ... #Management #Hematology
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