14 results
diagnosis treatment hyperkalemia potassium activetb causes diabetes high latenttb medications nephrology tb toxicity tuberculosis acromegaly allopurinol anthracycline antidote bisphosphonates cardiology
DPP4 Inhibitors - Normal and Renal Dosing Increase Incretins (GLP-I & GIP) -> Stimulates Insulin, Inhibits Glucagon
Normal and Renal Dosing ... This drug class ... #Pharmacology #Management ... #Diabetes #DM2 ... #Endocrinology
Mechanisms of Drug-Induced Hyperkalemia • Direct renin inhibitor (Aliskiren) • Renin release inhibition (NSAIDs, Beta-Blockers)
Mechanisms of Drug-Induced ... • Direct renin inhibitor ... #hyperkalemia #differential ... #diagnosis #pathophysiology ... #pharmacology #
SGLT2 Inhibitors SGLT2 inhibitors are the newest class of anti-diabetic medications, with the first one (Canagliflozin)
SGLT2 Inhibitors ... SGLT2 inhibitors ... #Pharmacology # ... Medications #DM2 ... #Diabetes #Endocrinology
Euglycemic Diabetic Ketoacidosis (EuDKA) SGLT2 Inhibitors Increasing Indications Significant Adverse Drug Effects Definition of EuDKA • Metabolic acidosis with pH
(EuDKA) SGLT2 Inhibitors ... Significant Adverse Drug ... level < 200 mg/dL Pathophysiology ... EuDKA #diagnosis #management ... #endocrinology
Bisphosphonates for Osteoporosis Treatment or Prevention Bisphosphonates are common medications used in the treatment and prevention
There are 4 drugs ... are a variety of dosing ... Schedule #Frequency #Pharmacology ... #Endocrinology ... #Osteoporosis #Management
Acromegaly - Diagnosis and Management Summary - GrepMed Handbook Clinical Presentation: • Classic Acromegaly: frontal
Acromegaly: frontal bossing ... malignancy Pathophysiology ... Differential Diagnosis ... pachydermoperiostosis, drugs ... #Endocrinology
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... Poorly controlled DM ... reactions Common Drugs ... NSAIDs • ACE Inhibitors
Hyperkalemia - Differential Diagnosis Framework PseudoHyperkalemia: • Lab error • Traumatic venipuncture • Hemolysis, thrombocytosis, leukocytosis •
Hyperkalemia - Differential ... Clenching of fist during ... Poorly controlled DM ... reactions Common Drugs ... NSAIDs • ACE Inhibitors
Allopurinol Pharmacology Summary Xanthine oxidase inhibitor blocking the formation of new uric acid Initiate 1-2 days prior to
Xanthine oxidase inhibitor ... chemotherapy Dosing ... : 100 mg/m2/dose ... hypersensitivity Drug ... #pathophysiology
Hemophagocytic Lymphohistiocytosis (HLH) Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Lymphohistiocytosis (HLH) Pathophysiology ... immune deficiency, Drugs ... Etoposide/VP16 (100 mg/m2 ... Anti-IFN-y and JAK inhibitors ... Lymphohistiocytosis #diagnosis #management
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