12 results
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... : >3 symptoms, or ... #APML #diagnosis ... #management #hematology
Polycythemia Vera (PV) - Diagnosis and Management Summary
Diagnostic Criteria:
 • Elevated hemoglobin and/or hematocrit AND
 •
Management Summary Diagnostic ... transformation into AML ... • Treatment algorithms ... von Willebrand disease ... #hematology
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
Infection in HIV / AIDS ... pathogens, including PML ... Antimicrobial treatment ... Hydrocephalus possible PML ... Demyelinating disease
Behçet's Syndrome
Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy
Epidemiology:
 • Young
meningitis), MCC CNS symptoms ... thrombosis, VTE) • Cardiac ... Arthritis, AS Treatment ... #signs #symptoms ... #rheumatology #
HIV-Associated Neurocognitive Disorder (HAND)

Definition:
HIV-Associated Neurocognitive disorders categories:
• Asymptomatic neurocognitive impairment
• Mild neurocognitive impairment
• HIV dementia

Pathophysiology:
HIV frequently
• Depressive symptoms ... is similar to PML ... well-defined than PML ... Diagnosis: MRI ... etiologies and PML
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
with no early symptoms ... cells can indicate disease ... microglobulin Treatment ... Transform to DLBCL, PML ... workup #oncology #hematology
Hepatopulmonary Syndrome - Diagnosis and Management Summary
A defect in arterial oxygenation due to a gas exchange
Hepatopulmonary Syndrome ... left heart 3-6 cardiac ... ) on room air Treatment ... resolution of symptoms ... #treatment #hepatology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Differential Diagnosis ... Malignancy (e.g. hematologic ... 5% of patients Cardiac ... Cytopenias • Cardiac ... Induced Lupus: • Symptoms
Immune Reconstitution Inflammatory Syndrome - Overview of IRIS

What Is IRIS?
	• A state of hyperinflammatory response that
Reconstitution Inflammatory Syndrome ... of HIV/AIDS patients ... worsening of that disease ... be present: • AIDS ... leukoencephalopathy (PML
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
age 70 years Symptoms ... Myeloproliferative Disease ... factor (GCSF) treatments ... marrow studies Treatment ... #diagnosis #hematology