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hematology disease erythematosus hemolytic lupus management signs systemic workup behcet cancer chronic cll cold coronavirus covid19 differential evaluation guide leukemia
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... of anemia include ... anemia • Cold ... disease #hemolytic #anemia ... #hematology #diagnosis
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... Algorithm • Sickle ... genotypes): SS, SC, SE ... Agglutination - Cold agglutinins ... aHUS, mechanical cardiac
Clinical Features of Systemic Lupus (SLE) General: Fever (50%), Depression, Fatigue (75%), Weight loss (50%) Eye: Sjögrens (15%) Skin
Clinical Features ... Systemic Lupus (SLE ... ) Blood (75%): Anemia ... erythematosus #signs #symptoms ... #diagnosis #rheumatology
Hematology Algorithms Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... Anemia is described ... experience some symptoms ... than 150,000 per mcL ... well as varying clinical
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... lymphopenia, low PLT • Anemia ... Induced Lupus: • Symptoms ... #Rheumatology
UCSF COVID-19 Adult Clinical Evaluation Guide - Updated April 10 2020 Clinical Presentation • Fever: hospitalized pts but
30%; can be only symptom ... 3-12% • Cardiac ... incr in 27-75% • PCT ... Evaluation #Guide #Diagnosis ... #Algorithm #Protocol
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
association • M > F Clinical ... thrombosis, VTE) • Cardiac ... Oral aphthae : SLE ... • Arthritis: SLE ... #rheumatology #
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
non-Hodgkin lymphoma SLL ... Orange or Hep C Clinical ... with no early symptoms ... phenomenon CLL Diagnosis ... • Neutropenia, anemia
Relapsing Polychondritis What is it? Recurrent inflammation of the cartilage in the body (Autoimmune disorder) Who? • Most frequently: 40
ethnicities Symptoms ... + Nonspecific symptoms ... cases such as: • SLE ... vessel aneurysms • Cardiac ... Polychondritis #rheumatology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
current treatment algorithm ... median age at diagnosis ... disease tolerate anemia ... importance of clinical ... #algorithm #hematology
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