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management syndrome oncology blood product reactions acute apml chronic cll comparison criteria dermatosis differential differentiation febrile leukemia leukostasis lymphocytic lysis
Leukostasis vs Tumor Lysis Syndrome Leukostasis: • Pathophysiology: Large, immature blasts and high WBC count cause hyperviscosity
tinnitus, visual changes ... lethargy, hematuria, cardiac ... with tetany or cardiac ... Syndrome #TLS #diagnosis ... #management #hematology
Diagnostic Criteria for Sweet Syndrome (Acute Febrile Neutrophilic Dermatosis) Major criteria 1. Abrupt onset of tender
Diagnostic Criteria ... an underlying hematologic ... Excellent response to treatment ... count >10 x 10^3/pL ... #Hematology #Dermatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Triggers: ATRA treatment ... opacities • Diagnosis ... Renal Failure Treatment ... fluid overload, PCC ... #management #hematology
SAPHO Syndrome Summary What? SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Sclerotic bone changes ... Nonspecific inflammatory changes ... and lower jaw Treatment ... SAPHO #Syndrome #Rheumatology ... #Dermatology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
phenomenon CLL Diagnosis ... microglobulin Treatment ... Transform to DLBCL, PML ... Lymphocytic #Leukemia #diagnosis ... workup #oncology #hematology
Scleroderma Like Conditions - Differential Diagnosis Eosinophilic Fasciitis: - Orange peel induration (peau d'orange) of proximal extremities
- Differential Diagnosis ... the mainstay of treatment ... contractures and/or cardiac ... #Differential #Diagnosis ... comparison #table #dermatology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Transfusion Cardiac ... , Trypanosoma (Chagas ... #Transfusion #diagnosis ... #management #hematology
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Transfusion Cardiac ... , Trypanosoma (Chagas ... #Transfusions #diagnosis ... #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
factor (GCSF) treatments ... cells have DNA changes ... marrow studies Treatment ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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