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Glomerular Diseases - Nephritic and Nephrotic Syndromes Nephritic syndrome—due to GBM disruption. Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... #Diseases #Nephritic ... #Proteinuria #Nephrology ... #Diagnosis
Nephritic vs Nephrotic Syndrome Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes. Step
the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology ... #Diagnosis
Atlas of Urine Microscopy Findings • Epithelial cells - Normal • Renal tubular cells - Acute
- Diagnostic of ... glomerular disease ... ” - Necrotic tubular ... Microscopy #Atlas #key #diagnosis ... #nephrology #casts
Intrinsic Renal Disease - Differential Diagnosis Vascular: • Macrovascular: Renal artery occlusion, Fibromuscular disease • Microvascular: TTP/HUS,
HTN, Vasculitis Glomerular ... : • Nephrotic: ... Antibiotics, NSAIDs, Cast ... #nephrology #differential ... #diagnosis
Urinary Casts and Disease Associations Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... and concentrated urine ... Advanced kidney disease ... Differential #Microscopy #Diagnosis ... #Nephrology
Causes of Hematuria - Differential Diagnosis Algorithm Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... blood cells on urine ... RBCs and/or RBC casts ... • Thin GBM disease ... • Pauci-immune disease
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
cell/white cell casts ... cluster, the diseases ... urine sediment ... #nephrotic #syndrome ... #nephrology
Urine Microscopy - Casts Acellular Casts • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... chronic kidney diseases ... suggestive of nephrotic ... #nephrology #interpretation ... #diagnosis
Recommended initial testing for patients being evaluated for glomerular disease 24-hour urine collection - Quantify proteinuria.
disease 24- ... Spot PC (protein ... in monitoring low-level ... testing #workup #diagnosis ... #nephritic #nephrology
Causes of Proteinuria - Differential Diagnosis Algorithm Persistent Proteinuria >150mg/d protein present on repeat testing including overnight
- Differential Diagnosis ... • Drugs Glomerular ... sediment - WBC/RBC casts ... Minimal change disease ... #Proteinuria #Nephrology
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