13 results
Glomerular Diseases - Nephritic and Nephrotic Syndromes

Nephritic syndrome—due to GBM disruption. 
Hypertension. t BUN and creatinine.
Glomerular Diseases ... RBC casts in urine ... #Diseases #Nephritic ... #Proteinuria #Nephrology ... #Diagnosis
Nephritic vs Nephrotic Syndrome

Step 1: If the patient has hematuria and/or proteinuria, think about nephrotic/nephritic syndromes.
Step
the patient have glomerular ... hematuria (RBC casts ... dysmorphic RBCs in urine ... Comparison #Algorithm #Nephrology ... #Diagnosis
Intrinsic Renal Disease - Differential Diagnosis
Vascular:
 • Macrovascular: Renal artery occlusion, Fibromuscular disease
 • Microvascular: TTP/HUS,
HTN, Vasculitis Glomerular ... : • Nephrotic: ... Amyloidosis, MPGN • Nephritic ... Antibiotics, NSAIDs, Cast ... #nephrology #differential
Urinary Casts and Disease Associations
Hyaline - May be nonspecific; seen in normal individuals or during severe
Disease Associations ... and concentrated urine ... tubulointerstitial nephritis ... tuberculosis Fatty - Nephrotic ... Differential #Microscopy #Diagnosis
Lupus Nephritis - Diagnostic approach to kidney disease associated with systemic lupus erythematosus (SLE)
SLE patient develops
Lupus Nephritis ... > 500 mg/d • Nephritic ... urine sediment ... 5%) #Lupus #Nephritis ... #sle #nephrology
Atlas of Urine Microscopy Findings
 • Epithelial cells - Normal
 • Renal tubular cells - Acute
- Diagnostic of ... glomerular disease ... ” - Necrotic tubular ... Microscopy #Atlas #key #diagnosis ... #nephrology #casts
Causes of Hematuria - Differential Diagnosis Algorithm
Red blood cells on urine microscopy. Must exclude false positives
- Differential Diagnosis ... blood cells on urine ... RBCs and/or RBC casts ... • Hereditary nephritis ... and >3.5g/day (nephrotic
Algorithm - Approach to the differential diagnosis of the patient presenting with overt glomerular proteinuria. CMV
cell/white cell casts ... clusters because nephritic ... urine sediment ... #nephrotic #syndrome ... #nephrology
Recommended initial testing for patients being evaluated for glomerular disease 

24-hour urine collection - Quantify proteinuria.
Spot PC (protein ... in monitoring low-level ... testing #workup #diagnosis ... glomerulonephritis #nephrotic ... #nephritic #nephrology
Urine Microscopy - Casts
Acellular Casts
 • Hyaline Casts - Consists of only precipitated Tamm-Horsfell protein without
Urine Microscopy ... chronic kidney diseases ... suggestive of nephrotic ... #nephrology #interpretation ... #diagnosis