14 results
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting, NGT
Primary Metabolic ... - Differential Diagnosis ... (late) • High Urine ... Bartter Syndrome, Gitelman ... #Algorithm #nephrology
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... - Differential Diagnosis ... (late) • High Urine ... Bartter Syndrome, Gitelman ... #Algorithm #Nephrology
Metabolic Alkalosis - Urinary Chloride Algorithm
Cl- responsive metabolic alkalosis
 • Kidney loss of Cl-
Bartter syndrome, Gitelman ... sodium is typically ... the excretion of sodium ... #Algorithm #nephrology ... #differential #diagnosis
Gitelman Syndrome Pathophysiology
Gitelman Syndrome is a rare autosomal recessive salt-losing tubulopathy with a prevalence of 1-
Gitelman Syndrome ... thiazide-sensitive sodium-chloride ... → Hypokalemia Metabolic ... Pathophysiology #nephrology ... #diagnosis
Inherited Defects in Kidney Tubule Epithelial Cells

Renal glucosuria - Na+-dependent glucose cotransporter
Cystinuria - Amino acid transporter
Bartter
ascending limb Gitelman ... cell epithelial sodium ... of epithelial sodium ... Defects #Kidney #Nephrology ... #Diagnosis #Differential
MRI Brain Sequence Comparison: T1 vs T2 vs FLAIR
T1:
 - CSF is Dark
 - Grey Matter
Brain Sequence Comparison ... Devpriyo Pal @drdevrad ... FLAIR #MRI #Brain #Comparison ... clinical #radiology #diagnosis ... #neurology
Cerebral Salt Wasting vs SIADH - Pathophysiology 
1) Neurological event
2) Sodium loss from tubules
3) Naturiesis →
Neurological event 2) Sodium ... → Increased urine ... Pathophysiology #diagnosis ... #nephrology #hyponatremia ... #comparison
Primary Metabolic Alkalosis - Differential Diagnosis Algorithm
Volume Depleted - 2° hyperaldosteronism
 • Low Urine Cl-: Vomiting,
Primary Metabolic ... - Differential Diagnosis ... (late) • High Urine ... Bartter Syndrome, Gitelman ... #Algorithm #Nephrology
Algorithm for patients with hypokalemia on the basis of the potassium-to-creatinine ratio in the urine
Urine K+
Cl - Non-reabsorbable ... Cl - Loop diuretics ... Bartter syndrome, Gitelman ... differential #algorithm #diagnosis ... #nephrology
Gitelman Syndrome Overview

What?
• Inherited (AR) hypokalemic salt-losing tubulopathies affecting the thiazide-sensitive sodium chloride cotransporter
• Gitelman's syndrome
thiazide-sensitive sodium ... thiazide-sensitive sodium ... Hypocalciuria (spot urine ... #Syndrome #diagnosis ... #nephrology #management