202 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... intralobular bile ducts ... failure PBC Signs ... No extrahepatic biliary ... malignancy #Primary #Biliary
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
— Normal Bile Ducts ... - Dilated Bile Ducts ... • Common Bile Duct ... Stone • Biliary
Myelopathy - Injury to the entire spinal cord - Signs and Symptoms
 • Ataxia (early sign)
spinal cord - Signs ... Ataxia (early sign ... weakness (late sign ... dexterity loss (early signs ... #symptoms #msk
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... gradual loss of bile ducts ... inflammation and biliary ... #PBC #Primary #Biliary
Diseases of the Biliary Tract
Asymptomatic gallstones - Asymptomatic
Symptomatic gallstones - Biliary pain
Cholesterolosis of gallbladder - Usually
Diseases of the Biliary ... Symptomatic gallstones - Biliary ... fever, Murphy sign ... cholecystitis - Biliary ... Asymptomatic or biliary
Primary Sjogren’s Syndrome: Pathogenesis and Clinical Findings
• Primary Sjögren's is a solitary process whereas secondary Sjögren's
processes like primary biliary ... erythematosus (SLE) Signs ... - Decreased mucous ... Pathophysiology #Diagnosis #Signs
Jaundice - Differential Diagnosis Algorithm
Pre-Hepatic - Unconjugated Hyperbilirubinemia
Increased Production
 • Hemolysis
 • Ineffective Erythropoiesis
 • Hematoma
Decreased
- Usually has Duct ... on Ultrasound Biliary ... Duct Compression ... Gallstones • Biliary
Cubital Tunnel Syndrome: Pathogenesis and clinical findings

 • Paresthesia of 5th and medial half of 4th
test • + Tinel sign ... • + Froment's sign ... + Wartenbergs sign ... pathophysiology #signs ... #symptoms #msk
Flexor Tenosynovitis (FTS)

The clinical diagnosis of FTS is made using Kanavel’s Signs:
 - Fusiform swelling.
 -
using Kanavel’s Signs ... Kanavels #Criteria #Sign ... #Hand #MSK #Diagnosis
Radiculopathy: Signs and Symptoms
 • Back/Neck Pain
 • Decr Range of motion
 • Abnormal posturing
 •
Radiculopathy: Signs ... • Spurling's sign ... pain Lasegue's sign ... Radiculopathy #MSK ... #diagnosis #signs