536 results
Patient factors influencing the selection Of glucose-lowering drugs Other than SGLT2i and metformin in T2D and
—4 inhibitor, eGFR ... sulfonylurea; T2D. type 2 diabetes ... type 2 diabetes; ... KDIGO2020 #CKD #Diabetes
Metformin 
Current Renal Dose Adjustments due to Risk of Lactic Acidosis 
> 60 No adjustment 
45-60
45-60 Monitor eGFR ... #Pharmacology #Diabetes
Management of Diabetes Mellitus in Patients With CKD

1. Monitor for changes in BP, serum creatinine, &
Management of Diabetes ... T2D, CKD, & an eGFR ... or Type 2 diabetes ... #Diabetes #CKD # ... ADA #KDIGO #eGFR
Metformin in Diabetic Kidney Disease
Immediate release:
 • Initial 500 mg or 850 mg once daily
 •
Metformin in Diabetic ... maximum dose eGFR ... recommended dose eGFR
Metformin Pharmacology Summary
Mechanisms of Action:
 • Suppresses gluconeogenesis by the liver
 • Increases insulin-mediated glucose utilization
not initiate if eGFR ... not continue if eGFR ... #Summary #DM2 #diabetes
SGLT2 Inhibitors - Pharmacology Summary
Mechanisms of Action: Inhibits SGLT2 (sodium/glucose cotransporter 2) in the proximal tubule,
Contraindications: eGFR ... • Euglycemic diabetic ... #Summary #DM2 #diabetes
Causes of Chronic Kidney Disease - Differential Diagnosis Algorithm
Decreased kidney function (eGFR < 60 ml/min/1.73 m2)
kidney function (eGFR ... Proteinuria) • Diabetes
ALBUMINURIA

•	Indicator of kidney damage and / or a biomarker of systemic diseases dates back to 1969,
newly diagnosed diabetes ... independent of eGFR ... cardiovascular #eGFR
The GFR Clock for Staging CKD

Staging CKD is most frequently done by calculating the estimated glomerular
The GFR Clock for ... function rate (eGFR ... calculating the eGFR ... to remember the eGFR ... #Nephro #CKD #EGFR
Summary of dosing recommendations in renal impairment of commonly used hypoglycaemic agents

#Diabetes #Diabetic #Medications #Pharmacology #Dosing
hypoglycaemic agents #Diabetes ... #Diabetic #Medications ... Impairment #CKD #Table #GFR