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rheumatology dermatology activation anemia bleeding cryofibrinogenemia cryoglobulins elevatedmcv enlarged macrocytic macrocytosis macrophage management mas naildisorders nonpalpable palpable purpura spleen splenomegaly
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
/ Bruising - Differential ... Diagnosis Algorithm ... Iatrogenic) • Liver ... Diagnosis #Algorithm ... #Causes #Hematology
Causes of Splenomegaly - Differential Diagnosis Algorithm Infectious • Bacterial • Viral (EBV) • Parasitic • Fungal Congestive
Diagnosis Algorithm ... Inflammatory • Systemic ... Lupus Erythematosus ... #Diagnosis #Algorithm ... #Causes #Hematology
Cryoglobulinemia Summary Cryoglobulins: • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Type III Often Secondary ... (e.g. systemic ... lupus erythematosus ... #types #classification
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... #Secondary #dermatology ... Diagnosis #Algorithm ... #causes
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... deficiency • Liver ... vasculitis/HSP • Cryoglobulinemia ... #Diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
Classified among the secondary ... (eg, systemic juvenile ... thrombocytopenia • Liver ... #Diagnosis #Management ... #Hematology #Rheumatology
Cryofibrinogenemia Summary Cryofibrinogenemia Epidemiology: • 40-70 years with a modest female predominance Cryofibrinogenemia: • The precipitation of a
Associated Disorders ... processes: • Systemic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
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