10 results
Causes of Splenomegaly - Differential Diagnosis Algorithm
Infectious
 • Bacterial
 • Viral (EBV)
 • Parasitic
 • Fungal
Congestive
Diagnosis Algorithm ... Inflammatory • Systemic ... Lupus Erythematosus ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Hypocomplementemia - CHAMPS Mnemonic
C - Cryoglobulinemia (85%), C3 glomerulopathy, cirrhosis
H - Heavy Chain deposition
Causes of Hypocomplementemia ... Chain deposition disease ... Lupus Erythematosus ... #differential # ... hematology
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm
Thrombocytopenia - Quantitative Defect
 • Decreased Production
 •
Diagnosis Algorithm ... Rare • Drugs (e.g ... Iatrogenic) • Liver ... #Diagnosis #Algorithm ... #Causes #Hematology
Cryoglobulinemia Summary

Cryoglobulins:
 • Cryoglobulins are Igs in the serum that precipitate in vitro at temperatures below
• Autoimmune diseases ... Type III Often Secondary ... (e.g. systemic ... lupus erythematosus ... #types #classification
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
Nail Disorders secondary ... to Systemic Diseases ... #Secondary #dermatology ... Diagnosis #Algorithm ... #causes
Purpura - Differential Diagnosis Framework

Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... Diagnosis Framework ... deficiency • Liver ... vasculitis/HSP • Cryoglobulinemia ... #Diagnosis #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Diagnosis Algorithm ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
Classification: ... permanent alopecia Differential ... . hematologic) ... (e.g. thyroid disease ... #Diagnosis #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
Associated Disorders ... processes: • Systemic ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology
Vasculitis and Vasculitides - Differential Diagnosis Framework

When to Consider Vasculitis:
 • Purpura, ischemic skin lesions
 •
tract, and often causes ... Diagnosis: Systemic ... against MPO • Complement ... #diagnosis #rheumatology ... #classification