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atlas common elevatedmcv extravascular gap globulin hemolysis hemolytic hypogammaglobulinemia immunodeficiency immunology intravascular macrocytic macrocytosis management mcv microscopy morphology naildisorders nomenclature
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
, Liver disease, ... Unstable hemoglobin disorders ... #Red #BloodCell ... RBC #Morphology #differential ... #diagnosis #hematology
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm ... Renal Disease, Liver ... Diagnosis #Algorithm ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Diagnosis Algorithm ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... IgA, IgG, IgM (CVID ... changes), high MCV anemia ... Diagnosis #Causes ... #Workup #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... . lupus, CLL, lymphoma ... lymphoproliferative disorders ... #differential # ... diagnosis #hematology
Nail Disorders secondary to Systemic Diseases Nail Fold Abnormality • SLE • Scleroderma • Dermatomyositis Koilonychia - Spoon-shaped
Nail Disorders secondary ... Iron deficiency anemia ... Systemic #Secondary #dermatology ... Diagnosis #Algorithm ... #causes
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disorder with hypogammaglobulinemia ... • Liver diseases ... autoimmune hemolytic anemia ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Connective tissue disorders ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... #diagnosis #hematology
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