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anemia bleeding hemolytic management oncology cold cvid elevatedmcv extravascular gap globulin hemolysis hemostasis hodgkins hypogammaglobulinemia immunology intravascular macrocytic macrocytosis mds
Causes of Bleeding / Bruising - Differential Diagnosis Algorithm Thrombocytopenia - Quantitative Defect • Decreased Production •
/ Bruising - Differential ... Diagnosis Algorithm ... Iatrogenic) • Liver ... Diagnosis #Algorithm ... #Causes #Hematology
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Secondary Cold ... Agglutinin Syndrome ... symptoms - most common ... younger pts) Differential ... #anemia #hematology
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
. lupus, CLL, lymphoma ... . primary cold agglutin ... disorders, Mycoplasma ... #differential # ... diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
- Differential ... Diagnosis Neonate ... - Immunodeficiency ... #diagnosis #causes ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Diagnosis Algorithm ... • Small Bowel Disorder ... Myelodysplastic Syndromes ... #Diagnosis #Algorithm ... #Causes #Hematology
Common Variable Immunodeficiency (CVID) What? CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
disorder with hypogammaglobulinemia ... infection risk secondary ... • Liver diseases ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
Bleeding and Bruising ... von Willebrand syndrome ... defects in the common ... discern these causes ... #Diagnosis #Hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
• Autoimmune disorders ... (NSHL) - (most common ... number of sites of disease ... #diagnosis #classification ... #hematology #oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... Comment on type ... #diagnosis #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Easy or unusual bruising ... Most common cytopenia ... DDX: Rule Out Secondary ... Myeloproliferative Disease ... #diagnosis #hematology
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