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algorithm hemolytic oncology abnormal ascites bleeding bruising coagulation disorders elevatedmcv gap globulin hemolysis hemostasis hodgkins intravascular lymphoma macrocytic macrocytosis management
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Causes Intravascular ... #Causes #differential ... #diagnosis #hematology ... #anemia
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Low Mean Corpuscular Volume (<80
Causes of Anemia ... Diagnosis Algorithm ... (e.g. ... #MCV #Classification ... #Causes #Hematology
Differential Diagnosis for Hemolytic Anemia Intrinsic Causes: • Enzyme deficiencies ex. G6PD, pyruvate kinase • Hemoglobinopathies
Differential Diagnosis ... : • Liver disease ... Diagnosis #causes ... #classification ... #hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... : INR/PT, aPTT(liver ... changes), high MCV anemia ... #Diagnosis #Causes ... #Workup #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm Normal Blood Smear •
Causes of Anemia ... Diagnosis Algorithm ... Increased Requirement (e.g ... Myelodysplastic Syndromes ... #Causes #Hematology
Causes of Abnormal PT and/or aPTT Prolonged Prothrombin Time (PT) 1. Acquired deficiency of FVII
Causes of Abnormal ... Early liver disease ... Disseminated intravascular ... #diagnosis #differential ... #hematology #coagulation
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
hallmark for the disease ... performed PT, PTT ... result in severe anemia ... WBC count and differential ... #Workup #Hematology
Ascites - Diagnostic Approach and Differential Diagnosis The most common causes: cirrhosis, malignancy and heart failure. Approx
most common causes ... (e.g. cirrhosis ... of underlying disease ... Jcortesizaguirr #Ascites #workup ... Diagnosis #hepatology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
of Hemostasis - Differential ... Diagnosis Framework ... von Willebrand syndrome ... discern these causes ... #Diagnosis #Hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
formed or don’t work ... Myeloproliferative Disease ... Workup: • Complete ... blood count with differential ... #diagnosis #hematology
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