11 results
Causes of Anemia by Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Low Mean Corpuscular Volume (<80
Causes of Anemia ... Disease (e.g. ... Hypothyroidism • Myelodysplasia ... #Anemia #MCV #Classification ... #Causes #Hematology
Causes of Thrombocytosis - Differential Diagnosis
Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis):
 • Acute infection
 • Solid organ
Diagnosis Secondary ... vera (PV) • Myelodysplastic ... syndrome • Myelofibrosis ... #Diagnosis #Causes ... #hematology #secondary
Diagnostic Framework for Anemia (Morphological Approach - MCV)
Low MCV - <80fL - "Microcytic"
 • Iron deficiency
Hypothyroidism, Myelodysplastic ... syndrome - Dr ... morphologic #mcv #differential ... #diagnosis #causes ... #hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Diagnosis Algorithm ... Dysplastic • Myelodysplastic ... Syndromes Macrocytosis ... #Causes #Hematology
Causes of Anemia with Low Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Decreased Heme Synthesis or
Diagnosis Algorithm ... Causes: Chronic ... 18% • Anemia Secondary ... HgbE, HgbC, etc. ... #Causes #Hematology
Nail Disorders secondary to Systemic Diseases
Nail Fold Abnormality
 • SLE
 • Scleroderma
 • Dermatomyositis
Koilonychia - Spoon-shaped
discoloration) • Chronic ... • Nephrotic syndrome ... #dermatology #Differential ... #Diagnosis #Algorithm ... #causes
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
infection risk secondary ... Autoimmunity • Chronic ... DDX - Other causes ... hypogammaglobulinemia #immunology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
DDX: Rule Out Secondary ... Marrow Failure • Chronic ... Myeloproliferative Disease ... #Syndromes #diagnosis ... #hematology #oncology
Macrophage Activation Syndrome (MAS)
Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH)

What?
A subset of
Classified among the secondary ... Systemic lupus erythematosus ... systemic lupus erythematosus ... #Diagnosis #Management ... #Hematology #Rheumatology
Cryofibrinogenemia Summary

Cryofibrinogenemia Epidemiology:
 • 40-70 years with a modest female predominance

Cryofibrinogenemia:
 • The precipitation of a
cryoglobulin (CG ... 2019 (COVID-19) ... cryoglobulins • Negative causes ... Antiphospholipid syndrome ... hematology