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oncology morphology rbc bleeding chronic extravascular gap globulin hemolysis hemolytic hemostasis hodgkins key lymphocytic lymphoma management mds microscopy myelodysplasia myelodysplastic
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Causes Intravascular ... . lupus, CLL, lymphoma ... . sickle cell disease ... #Causes #differential ... #diagnosis #hematology
Red Blood Cell (RBC) Morphology Microcytic RBC: Pyridoxine deficiency, Thalassemia, Iron deficiency anemia, Chronic disease anemia (sometimes),
Red Blood Cell ( ... Unstable hemoglobin disorders ... #Red #BloodCell ... #diagnosis #hematology ... #microscopy #atlas
Red Blood Cell (RBC) Morphology Atlas • Microcytic - Iron-deficiency anemia, Thalassemia, Sideroblastic anemia, Lead poisoning
Red Blood Cell ( ... Malignant tumors, Acute ... #key #diagnosis ... #differential # ... hematology
Causes of Thrombocytosis - Differential Diagnosis Secondary Thrombocytosis (a.k.a Reactive Thrombocytosis): • Acute infection • Solid organ
Thrombocytosis): • Acute ... malignancies • Anemia ... Myelodysplastic syndrome ... #Diagnosis #Causes ... #hematology #secondary
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... extramedullary disease ... - infiltrates (anemia ... #Hematology #Oncology ... #Diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
cells can indicate disease ... • Neutropenia, anemia ... microglobulin Treatment ... ’s lymphoma or acute ... #oncology #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
caused by blood ... cell count (anemia ... Easy or unusual bruising ... Cell Leukemia ... #diagnosis #hematology
Causes of Neutropenia - Differential Diagnosis Neonate: - Infection - by far the most common cause -
hypertension and/or drug treatment ... Megaloblastic anemia-rare ... including white blood ... #diagnosis #causes ... #hematology
Bleeding and Bruising - Disorders of Hemostasis - Differential Diagnosis Framework == Quantitative or Qualitative defect in
gingivitis or gingival leukemic ... von Willebrand syndrome ... , disseminated intravascular ... discern these causes ... #Diagnosis #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
changes (POEMS syndrome ... Connective tissue disorders ... gastric tumors • Hematology ... anemia • Other ... #diagnosis #hematology
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